Searchable abstracts of presentations at key conferences on calcified tissues

ba0002op13 | (1) | ICCBH2013

Long-term effects of bisphosphonate therapy in children with osteogenesis imperfecta

Biggin Andrew , Zheng Linda , Briody Julie , McQuade Mary , Munns Craig

Objectives: To evaluate the clinical outcomes of intravenous bisphosphonate treatment in children with mild-moderate osteogenesis imperfecta (OI) who had progressed from active bisphosphonate treatment to maintenance therapy for >2 years.Methods: A retrospective review was conducted on 17 patients with mild-moderate OI. Clinical data, fracture history, biochemistry, dual energy X-ray absorptiometry (DXA) parameters, vertebral measurements, bone age a...